HLA testing may be suggested for children with seizure disorders in higher-risk ethnic groups. Children who test positive for the HLA-B*1502 allele should not take which common anti-seizure medication because of their increased risk of developing Stevens-Johnson syndrome?

Question

Quizplus · Accepted Answer

Carbamazepine is associated with an increased risk of Stevens-Johnson syndrome in individuals who test positive for the HLA-B*1502 allele, particularly in certain Asian populations. This genetic testing can help guide safer medication choices for those with seizure disorders.

HLA Testing May Be Suggested for Children with Seizure Disorders