Which is defined by being chronic and a marked loss of pleasure in all or almost all activities every day or most of the days in a 2-week period along with four other symptoms, such as feelings of worthlessness, over the same time period as determined in the DSM-V?

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Major depressive disorder is characterized by a persistent feeling of sadness and loss of interest, including a marked loss of pleasure in activities, along with other symptoms such as feelings of worthlessness, as defined in the DSM-V.

Which Is Defined by Being Chronic and a Marked Loss