The CREATE randomized trial compared an antidepressant, citalopram, to a placebo used alongside interpersonal therapy (IPT) in cardiovascular patients. The results show that the antidepressant ________ and that the IPT ________.

Question

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The CREATE trial found that citalopram effectively reduced the symptoms of depression in cardiovascular patients, while interpersonal therapy (IPT) did not show a significant effect in reducing depression symptoms compared to the control conditions.

The CREATE Randomized Trial Compared an Antidepressant, Citalopram, to a Placebo