To Maintain a Constant Steady-State High Sensitivity Level of Muscle

To maintain a constant steady-state high sensitivity level of muscle ACh,

A) muscle must be constantly active.
B) muscle must undergo intermittent naturally occurring denervation.
C) ACh receptors must cluster as discrete sites at the end-plates.
D) ACh receptors must reliably turnover (be regularly synthesized and degraded) .
E) Acetylcholinesterase must be inhibited.