Ion Selectivity of Cys-Loop and Voltage-Activated Ion Channels Depends

Ion selectivity of Cys-loop and voltage-activated ion channels depends

A) inversely on the number of subunits (i.e., fewer subunits means higher ion specificity) .
B) directly on the number of subunits (i.e., more subunits means higher ion specificity) .
C) on properly spaced charged amino acids in the primary structure of the channel proteins.
D) on auxiliary subunits (e.g., β-subunits) , which associate with the main (α) subunit of the channel.
E) on the P-loop.