MHC expression is constitutive; however, levels of MHC I and II can vary depending on conditions.Which of the following is NOT known to influence MHC expression levels?

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Quizplus · Accepted Answer

All the options listed are known to influence MHC expression levels. CIITA is a transactivator for MHC class II genes, and CITA, though less commonly referenced, is implied to be related to MHC expression regulation. Hepatitis B infection can alter MHC expression as part of the immune response. IL-4 is a cytokine that can modulate immune responses, including MHC expression. Corticosteroids are known to suppress immune responses, which can include downregulation of MHC molecules.

MHC Expression Is Constitutive; However, Levels of MHC I and II