Which of the following would you predict to result from a mutation in TLR4 that prevents binding to LPS?

Question

Quizplus · Accepted Answer

TLR4 is a receptor involved in the immune response to lipopolysaccharides (LPS), which are components of the outer membrane of gram-negative bacteria. A mutation in TLR4 that prevents binding to LPS would likely result in decreased activation of the immune response to these bacteria, potentially reducing the risk of septic shock, a severe reaction to bacterial infection.

Which of the Following Would You Predict to Result from a Mutation