Match the following toll-like receptors with their ligands. $\begin{array}{ll}
\text { TLR } & \text { Ligands } \
\hline \text { TLR3 } & \text { Flagellin } \
\text { TLR4 } & \text { Zymosan } \
\text { TLR5 } & \text { dsRNA } \
\text { TLR6 } & \text { CpG unmethylated dinucleotides } \
\text { TLR9 } & \text { LPS }
\end{array}$

Question

Quizplus · Accepted Answer

TLR3 is known to recognize double-stranded RNA (dsRNA), a molecule often found in viruses. TLR4 recognizes lipopolysaccharides (LPS), which are components of the outer membrane of Gram-negative bacteria. TLR5 binds to flagellin, a protein that makes up the bacterial flagellum. TLR6 forms heterodimers with TLR2 to recognize diacylated lipopeptides, but zymosan, a component of fungal cell walls, is recognized by TLR2 in conjunction with TLR6. TLR9 is known for its ability to recognize unmethylated CpG dinucleotides, which are prevalent in bacterial and viral DNA but rare in vertebrate DNA.

Match the Following Toll-Like Receptors with Their Ligands A)TLR3/LPS; TLR4/CpG Unmethylated Dinucleotides; TLR5/dsRNA; TLR6/Zymosan; TLR9/Flagellin B)TLR3/dsRNA; TLR4/LPS; TLR5/Flagellin;

Match the Following Toll-Like Receptors with Their Ligands A)TLR3/LPS; TLR4/CpG Unmethylated Dinucleotides; TLR5/dsRNA; TLR6/Zymosan; TLR9/Flagellin
B)TLR3/dsRNA; TLR4/LPS; TLR5/Flagellin;