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How Can Anti-CD20 Monoclonal Antibodies Be Used to Fight the Malignant

Question 30

Multiple Choice

How can anti-CD20 monoclonal antibodies be used to fight the malignant cells of Non-Hodgkin's lymphoma if both healthy and cancerous B cells possess CD20 on their surfaces?


A) The monoclonal antibodies have a higher affinity for binding the malignant B cells, allowing them to be selectively eliminated.
B) Both groups of B cells are destroyed by the monoclonal antibodies, but host damage is minimal as stem cells are unaffected and quickly generate more healthy B cells.
C) The monoclonal antibodies preferentially bind and destroy the stem cells responsible for producing the malignant B cells.
D) The monoclonal antibodies effectively eliminate malignant and healthy B cells, but the host is not negatively affected because their level of T cells increases to compensate for the lost B cells.

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