This antiviral agent is a nonnucleoside drug that is a noncompetitive inhibitor of HIV reverse transcriptase It is used in combination therapy to treat patients with varying stages of HIV infections. It is effective against HIV-1 virus infections, but not HIV-2 infections.

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Efavirenz is a nonnucleoside reverse transcriptase inhibitor (NNRTI) used in combination therapy for the treatment of HIV-1 infections. Unlike nucleoside reverse transcriptase inhibitors (NRTIs), NNRTIs like Efavirenz bind directly to reverse transcriptase at a site distinct from the active site, causing noncompetitive inhibition. It is not effective against HIV-2.

This Antiviral Agent Is a Nonnucleoside Drug That Is a Noncompetitive