Question 1

Melissa is to have 1.5 grams of drug A/day, to be given 4/24. Stock available is 125 mg scored tablets. The number of tablets/dose that should be given is

Accepted Answer

Melissa needs 1.5 grams per day, which is 1500 mg. Given 4 doses per day, each dose is 375 mg (1500 mg / 4). Each tablet is 125 mg, so 375 mg requires 3 tablets (375 mg / 125 mg per tablet).

Question 2

Suzie is to have 0.25 mg of drug B per day, to be given 6/24. Stock available is 62.5 mcg tablets. For a single dose she should receive

Accepted Answer

D

Question 3

Mr Wilkinson is to have 75 mg of drug C. Stock in the ward is 100 mg/2 ml. The volume of drug C required for this order is

Accepted Answer

To calculate the volume of drug C required for a 75 mg dose, use the concentration of the stock solution (100 mg/2 ml). The formula is (desired dose / stock concentration) * stock volume. So, (75 mg / 100 mg) * 2 ml = 1.5 ml.

Question 4

Mrs Cook is to have 7500 units of drug D. Stock in the ward is 5000 units/0.2 ml. The volume required for this order is

Accepted Answer

To find the volume required, use the formula: (Desired dose / Stock dose) x Stock volume. Here, (7500 units / 5000 units) x 0.2 ml = 0.3 ml.

Question 5

Tommy, who weighs 15 kg, is to have 20 mg/kg/day of drug E. This medication is to be given 8/24. Stock is 125 mg/5 ml. For a single dose you should pour

Accepted Answer

The answer of Tommy, who weighs 15 kg, is to...

Question 6

Claire is to have 1 gram of drug F per m² of BSA per day, to be given in two equally divided doses. Claire's BSA is 0.6 m² and drug F is available as a mixture of 125 mg/5 ml. The volume of drug F required for a single dose is

Accepted Answer

The answer of Claire is to have 1 gram of...

Question 7

Chris is to have 800 mg of drug G which is available as 1 gram of powder in a 10 ml vial. When reconstituted, drug G will displace 0.7 ml of fluid. The amount of sterile fluid
Required to reconstitute drug G to a concentration of 200 mg/1 ml is

Accepted Answer

The answer of Chris is to have 800 mg of...

Question 8

Drug H is to be reconstituted to a concentration of 250 mg/ml. Drug H is also available as 1 gram of powder and will displace 1 ml of fluid on reconstitution. The volume of sterile fluid required for this order is

Accepted Answer

1 gram of powder will displace 1 ml of fluid on reconstitution. So, 250 mg of powder will displace 0.25 ml of fluid. Therefore, the volume of sterile fluid required for this order is 4 ml (250 mg/ml x 0.25 ml = 4 ml).

Question 9

Nellie has an intravenous infusion in which 90 ml remain in the bag. This infusion is dripping at the rate of 45 drops minute via a drop factor of 20 drops/ml. The number of minutes that this infusion will take to complete is

Accepted Answer

The infusion will take 90 ml / (45 drops/minute * 20 drops/ml) = 100 minutes to complete.

Question 10

James has 50 ml of intravenous fluid left in the 0.5 L bag. This fluid is dripping at 40 drops/minute via a micro-dropper. Time taken to complete this infusion will be

Accepted Answer

The answer of James has 50 ml of intravenous fluid...

Question 11

Susan is receiving an infusion at the rate of 2 ml/minute via a line with a drop factor of 20 drops/ml. The number of drops/minute that would deliver 2 ml are

Accepted Answer

To find the number of drops per minute that would deliver 2 ml, you multiply the infusion rate (2 ml/minute) by the drop factor (20 drops/ml). So, 2 ml/minute * 20 drops/ml = 40 drops/minute.

Question 12

Mary's infusion is dripping at the rate of 45 drops/minute, via a micro-dropper. The volume per hour that Mary is receiving from this infusion is

Accepted Answer

A micro-dropper typically delivers 60 drops per milliliter. Therefore, at 45 drops per minute, Mary receives 45/60 ml per minute, which equals 0.75 ml per minute. Over an hour, this amounts to 0.75 ml/min * 60 min = 45 ml/hour.

Question 13

8 ml of medication has been added to 42 ml of fluid in the burette on Ron's infusion line. The drop factor for this line is 20 drops/ml. This medicated solution is to infuse over 15 minutes so the rate of flow in drops/minute should be

Accepted Answer

The total volume of the solution is 8 ml (medication) + 42 ml (fluid) = 50 ml. With a drop factor of 20 drops/ml, the total number of drops is 50 ml * 20 drops/ml = 1000 drops. To infuse this over 15 minutes, the rate is 1000 drops / 15 minutes = 66.67 drops/minute, which rounds to 67 drops/minute.

Question 14

Olive has a medicated infusion of 60 ml which is to complete in 40 minutes. The drop factor for this line is 20 drops/ml. The number of drops/minute should be

Accepted Answer

To calculate the number of drops per minute, first find the total number of drops in the infusion: 60 ml * 20 drops/ml = 1200 drops. Then, divide by the total time in minutes: 1200 drops / 40 minutes = 30 drops/minute.

Question 15

Mrs Rome has a medicated infusion with 60 mg of drug J in 60 ml of fluid. This solution is to infuse at the rate of 2.5 ml/hour, after commencing with a bolus dose of 5 mg over 4 minutes. The ml/hour required for this bolus dose is

Accepted Answer

To calculate the ml/hour required for the bolus dose, first determine the concentration of the drug in the solution, which is 60 mg in 60 ml, or 1 mg/ml. For a 5 mg bolus dose, 5 ml of the solution is needed (since 1 mg is in 1 ml). To administer this over 4 minutes, convert the time to hours (4 minutes = 4/60 hours = 1/15 hours). The rate in ml/hour is then 5 ml divided by 1/15 hours, which equals 75 ml/hour.

Question 16

Mr Lennard has a medicated infusion with 450 mg of drug K in 100 ml of fluid. This solution is delivering 4 ml/hour. A bolus dose of 18 mg is to be given over a 3-minute period. The ml/hour required for this bolus dose is

Accepted Answer

The answer of Mr Lennard has a medicated infusion with...

Question 17

Jason, who weighs 60 kg, has been ordered 150 mg/kg of drug L, to be given intravenously over a 30-minute period. Stock in the department is a 20% solution of drug
L in a 250 ml bag of fluid. The volume/hour required for this 30-minute order is

Accepted Answer

First, calculate the total dose required for Jason: 150 mg/kg * 60 kg = 9000 mg. The stock solution is 20%, meaning there are 20 grams of drug L in 100 ml of solution, or 200 grams in 1000 ml (1 liter). Since 9000 mg is equal to 9 grams, we need to find out how much of the 20% solution will provide 9 grams of drug L. If 200 grams are in 1000 ml, 9 grams are in (9/200) * 1000 ml = 45 ml. Since the medication needs to be administered over 30 minutes and the total volume that contains the required dose is 45 ml, to find the rate in ml/hour, we double it (because 30 minutes is half an hour), resulting in 90 ml/hour.

Question 18

Mr Tate, who weighs 80 kg, is to have 200 mg/kg of drug M, to be given intravenously over 45 minutes. Stock on hand is a 10% solution in 250 ml. The volume/hour required for this 45-minute order is

Accepted Answer

First, calculate the total mg of drug M needed for Mr. Tate: 80 kg * 200 mg/kg = 16,000 mg. A 10% solution means 10 g of drug per 100 ml, so 250 ml contains 25 g or 25,000 mg. To get the volume of solution needed to deliver 16,000 mg: (16,000 mg / 25,000 mg) * 250 ml = 160 ml. Since this volume needs to be administered over 45 minutes, to find the rate in ml/hour: (160 ml / 45 min) * 60 min/hour = 213.3 ml/hour.

Question 19

Clive, who weighs 75 kg, has been ordered drug N at the rate of 3 mcg/kg/minute. The prepared solution contains 50 mg of drug N in 250 ml of fluid. The volume/hour required for this order is

Accepted Answer

First, calculate the total mcg/min ordered for Clive: 3 mcg/kg/min * 75 kg = 225 mcg/min. Next, convert the total amount of drug in the solution from mg to mcg: 50 mg = 50,000 mcg. To find out how many mcg per ml the solution has, divide the total mcg by the volume of the solution: 50,000 mcg / 250 ml = 200 mcg/ml. To find out how many ml/min Clive needs to receive the ordered dose, divide the ordered mcg/min by the concentration of the solution in mcg/ml: 225 mcg/min / 200 mcg/ml = 1.125 ml/min. Finally, to convert ml/min to ml/hour, multiply by 60: 1.125 ml/min * 60 = 67.5 ml/hour.

Question 20

Elizabeth is to receive an infusion of 1250 units of drug P/hour. Prepared stock is 25 000 units in a 500 ml solution. The ml/hour required for this order would be

Accepted Answer

To find the ml/hour, first determine the concentration of the drug: 25,000 units in 500 ml means 50 units/ml. To deliver 1250 units/hour, divide 1250 by 50, which equals 25 ml/hour.

Quiz 6: Complex Calculations