Jason, who weighs 60 kg, has been ordered 150 mg/kg of drug L, to be given intravenously over a 30-minute period. Stock in the department is a 20% solution of drug
L in a 250 ml bag of fluid. The volume/hour required for this 30-minute order is
A) 90 ml
B) 60 ml
C) 45 ml
D) 30 ml

Question

Quizplus · Accepted Answer

First, calculate the total dose required for Jason: 150 mg/kg * 60 kg = 9000 mg. The stock solution is 20%, meaning there are 20 grams of drug L in 100 ml of solution, or 200 grams in 1000 ml (1 liter). Since 9000 mg is equal to 9 grams, we need to find out how much of the 20% solution will provide 9 grams of drug L. If 200 grams are in 1000 ml, 9 grams are in (9/200) * 1000 ml = 45 ml. Since the medication needs to be administered over 30 minutes and the total volume that contains the required dose is 45 ml, to find the rate in ml/hour, we double it (because 30 minutes is half an hour), resulting in 90 ml/hour.

Jason, Who Weighs 60 Kg, Has Been Ordered 150 Mg/kg