A Primary Care NP Is Preparing to Prescribe a Drug

A primary care NP is preparing to prescribe a drug and notes that the drug has nonlinear kinetics.The NP should:

A) monitor frequently for desired and adverse effects.
B) administer a much higher initial dose as a loading dose.
C) monitor creatinine clearance at baseline and periodically.
D) administer the drug via a route that avoids the first-pass effect.