Second pain is a throbbing, burning, radiating sensation that is not as localized as first pain. Second pain also has more impact on learning and motivation than first pain.

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Second pain, mediated by slower-conducting C fibers, is characterized by a throbbing, burning, radiating sensation that is less localized than the sharp, immediate pain (first pain) transmitted by faster A-delta fibers. This second pain is more closely associated with emotional processing and can have a greater impact on learning and motivation, as it is processed by the brain in a way that contributes to the avoidance of similar painful stimuli in the future.

Second Pain Is a Throbbing, Burning, Radiating Sensation That Is