The consequences of a recessive metabolic disorder such as PKU can be counteracted with a modification in dietary intake,making PKU a good example of

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PKU is a recessive metabolic disorder caused by a mutation in the gene coding for phenylalanine hydroxylase, leading to the accumulation of phenylalanine and its toxic by-products in the blood and brain. The dietary modification involves restricting the intake of phenylalanine to prevent its build-up, which can cause intellectual disability, seizures, and behavioral problems. This illustrates how the individual's genotype (having two copies of the mutated gene) interacts with the environment (the intake of phenylalanine) to affect the phenotype (the symptoms of PKU). By modifying the environment (the diet), the harmful effects of the genotype can be reduced or eliminated, highlighting the interaction between the genotype and environment in determining the phenotype.

The Consequences of a Recessive Metabolic Disorder Such as PKU