Frederick was born with an anomaly on his X chromosome,but he displays no symptoms.If this mutation is passed on to his children,who is most likely to display full-blown fragile X syndrome according to the phenomenon of anticipation?

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Fragile X syndrome is an X-linked dominant disorder, meaning that males (who have only one X chromosome) are more severely affected than females (who have two X chromosomes). In males, the mutation on the X chromosome is fully expressed, leading to the full-blown fragile X syndrome. In females, the mutation is partially expressed, leading to a milder form of the disorder known as fragile X premutation. However, the phenomenon of anticipation means that the severity of the disorder tends to increase with each generation. This is because the mutation on the X chromosome becomes more expanded with each generation, leading to a more severe form of the disorder. Therefore, Frederick's grandson is most likely to display full-blown fragile X syndrome, as the mutation on the X chromosome will have had more time to expand and become more severe.

Frederick Was Born with an Anomaly on His X Chromosome,but