Drugs can alter CNS neurotransmission by affecting neurotransmitter

Question

Quizplus · Accepted Answer

Drugs can affect neurotransmitter synthesis by blocking or enhancing the enzymes responsible for their production in the presynaptic terminal. They can affect neurotransmitter release by either promoting or inhibiting exocytosis of the neurotransmitter-containing vesicles. Drugs can also affect neurotransmitter degradation at the synapse by blocking the enzymes responsible for breaking them down, or they can enhance their breakdown by increasing the activity of these enzymes. Finally, drugs can affect neurotransmitter reuptake into the presynaptic terminal by blocking the transporters responsible for their reuptake, leading to increased extracellular levels of the neurotransmitter. Therefore, all of the options listed are true.

Drugs Can Alter CNS Neurotransmission by Affecting Neurotransmitter