On the histologic grading scale for tumors,which grade is the worst?

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Grade 3 is considered the worst on the histologic grading scale, as it indicates a high degree of abnormal cells and likelihood of aggressive growth and spread. Grades 0, 1, and 2 indicate increasingly less abnormal cells and lower likelihood of aggressive behavior. The staging of a tumor is a separate evaluation based on factors such as size, involvement of nearby tissues, and distant metastases.

On the Histologic Grading Scale for Tumors,which Grade Is the Worst