The plasma clearance of a substance can be used to calculate the glomerular filtration rate (GFR) if that substance is freely filtered at the glomerulus and _____________
A)secreted and reabsorbed by the tubules.
B)neither reabsorbed nor secreted by the tubules.
C) secreted by the tubules but not reabsorbed by the tubules.
D) reabsorbed by the tubules but not secreted by the tubules.

Question

Quizplus · Accepted Answer

If a substance is freely filtered at the glomerulus and neither reabsorbed nor secreted by the tubules, then the plasma clearance of that substance would equal the GFR. This is because all of the substance that enters the kidney through the glomerulus would be excreted in the urine without any additional contribution from tubular secretion or reabsorption.

The Plasma Clearance of a Substance Can Be Used to Calculate