A mutation occurs that changes a C to a T in DNA such that, in the mRNA transcribed from this piece of DNA, a UGG codon is changed to UGA. This mutation is a
A) substitution mutation.
B) missense mutation.
C) nonsense mutation.
D) substitution mutation and a missense mutation.
E) substitution mutation and a nonsense mutation.

Question

Quizplus · Accepted Answer

The mutation is a substitution mutation because one nucleotide is replaced by another. It is also a nonsense mutation because the UGG codon, which codes for tryptophan, is changed to UGA, a stop codon, leading to premature termination of translation.

A Mutation Occurs That Changes a C to a T