Products of tumor-suppressor genes act at control points in the cell cycle.

Question

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Tumor-suppressor genes code for proteins that regulate cell growth and division. These proteins act at various control points in the cell cycle, such as the G1 checkpoint, to prevent cells with damaged DNA from entering the S phase and replicating their DNA. When these genes are mutated or lost, cells can divide uncontrollably and form tumors. Therefore, products of tumor-suppressor genes do act at control points in the cell cycle.

Products of Tumor-Suppressor Genes Act at Control Points in the Cell