Membranoproliferative glomerulonephritis caused by mixed cryoglobulinemia is most often secondary to which of the following diseases?
A) Diabetes mellitus
B) Multiple myeloma
C) Membranous nephropathy
D) Amyloidosis
E) Human immunodeficiency virus infection

Question

Quizplus · Accepted Answer

Membranoproliferative glomerulonephritis caused by mixed cryoglobulinemia is most often a complication of viral hepatitis C. The glomeruli contain deposits of IgG-IgM cryoglobulins, which are also found in the small blood vessels of the skin and joints, resulting in cutaneous vasculitis with petechial hemorrhages and synovitis.

Membranoproliferative Glomerulonephritis Caused by Mixed Cryoglobulinemia Is Most Often Secondary