Hypofrontality is demonstrated by the poor performance of schizophrenics on the Wisconsin Card Sorting Test.

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Hypofrontality refers to reduced activity in the prefrontal cortex of the brain, and schizophrenia is associated with hypofrontality. The Wisconsin Card Sorting Test (WCST) measures cognitive flexibility, which is thought to be mediated by the prefrontal cortex. Schizophrenics often perform poorly on the WCST, which is evidence of hypofrontality.

Hypofrontality Is Demonstrated by the Poor Performance of Schizophrenics on the Wisconsin