Matching
Match each of the following descriptions in questions with the appropriate disease (A-G).
-Defect in lymphocyte activation due to mutations in the gene encoding the SAP adapter protein required for inhibition of signaling by the SLAM molecule. Lack of SAP results in uncontrolled B cell proliferation, hypogammaglobulinemia, and B cell lymphoma in the setting of Epstein-Barr virus (EBV) infection.
A)X-linked agammaglobulinemia
B)X-linked hyper-IgM syndrome
C)X-linked lymphoproliferative syndrome
D)Bare lymphocyte syndrome
E)Chronic granulomatous disease (CGD)
F)Leukocyte adhesion deficiency-1 (LAD-1)
G)Leukocyte adhesion deficiency-2 (LAD-2)

Question

Quizplus · Accepted Answer

X-linked lymphoproliferative syndrome is characterized by a severe CD8⁺ T cell response to Epstein-Barr virus (EBV), the virus that causes infectious mononucleosis
In a way, this is an example of a lethal exaggerated response to an infection, rather than a true immunodeficiency.

Matching Match Each of the Following Descriptions in Questions with the the Appropriate