Matching Match the definitions in questions with the mast cell mediator (A-G) that most closely matches it. -Cyclooxygenase-pathway product of arachidonic acid metabolism that causes vascular dilatation, smooth muscle contraction, and neutrophil chemotaxis A)Histamine B)Tryptase C)Prostaglandin D₂ D)Leukotriene C₄ E)Platelet-activating factor F)Interleukin-5 G)Tumor necrosis factor-a

Question

Quizplus · Accepted Answer

Prostaglandin D₂ (PGD₂) is the major arachidonic acid product of the cyclooxygenase pathway in mast cells
PGD₂ causes vasodilation and bronchoconstriction, which contribute to the early signs and symptoms of immediate hypersensitivity reactions
It also is a chemoattractant for neutrophils, which accumulate in tissues as part of the late-phase inflammatory response to allergens.

Matching Match the Definitions in Questions with the Mast Cell Mediator