Matching Match the definitions in questions with the mast cell mediator (A-G) that most closely matches it. -Soluble factor that promotes inflammation and late-phase reaction and activates endothelial expression of adhesion molecules critical for sequential neutrophilic infiltrate A)Histamine B)Tryptase C)Prostaglandin D₂ D)Leukotriene C₄ E)Platelet-activating factor F)Interleukin-5 G)Tumor necrosis factor-a

Question

Quizplus · Accepted Answer

When tumor necrosis factor-a is released during IgE-mediated mast cell activation, it activates endothelial expression of the adhesion molecules, accounting for subsequent infiltration of neutrophils
As such, it is critical for inflammation and the late-phase allergic reaction.

Matching Match the Definitions in Questions with the Mast Cell Mediator