The figure depicts the germline organization of gene segments of the Ig heavy chain locus on chromosome 14.
Choose the lettered label on the figure (A-E) that best matches the description in questions .

-A segment that encodes Ig-like domains that form part of the antigen-binding region of an Ig molecule

Question

The figure depicts the germline organization of gene segments of the Ig heavy chain locus on chromosome 14.
Choose the lettered label on the figure (A-E) that best matches the description in questions .
 
-A segment that encodes Ig-like domains that form part of the antigen-binding region of an Ig molecule

Quizplus · Accepted Answer

The Answer is A
One variable (V) gene segment, from as many as 45 possible V gene segments, is used in each functional Ig heavy chain gene
This V gene segment encodes an Ig domain that includes complementarity-determining regions (CDRs) 1 and 2 of the antigen-binding region of the heavy chain.

The Figure Depicts the Germline Organization of Gene Segments of the Ig