The progression from metaphase to anaphase results from
A) phosphorylation mediated by Polo-like kinase.
B) ubiquitin-mediated proteolysis of key regulatory proteins.
C) phosphorylation mediated by Cdk2.
D) activation by Wee1.

Question

Quizplus · Accepted Answer

The progression from metaphase to anaphase is triggered by the degradation of key regulatory proteins such as cyclin B and securin. This degradation is mediated by the addition of ubiquitin molecules by the anaphase-promoting complex/cyclosome (APC/C).

The Progression from Metaphase to Anaphase Results from