The GTP on the G protein that is linked to adenylyl cyclase is split to GDP and P_i A) in the inactive state. B) in the process of subunit separation. C) upon activation by the receptor. D) by the active $\alpha$ subunit.

Question

Quizplus · Accepted Answer

The GTP on the G protein is split to GDP and Pi by the active Gα subunit, which is part of the process that turns off the signal transduction pathway initiated by the G protein. This hydrolysis of GTP to GDP is what inactivates the Gα subunit, allowing it to reassociate with the Gβγ subunits and return the G protein to its inactive state.

The GTP on the G Protein That Is Linked to Adenylyl