Mutations in the genes for RAG1 and RAG2 would most likely have an effect on
A) VDJ recombination in the immune system.
B) mismatch repair.
C) excision repair.
D) translesion DNA synthesis.

Question

Quizplus · Accepted Answer

RAG1 and RAG2 genes are involved in the development of the immune system by facilitating VDJ (variable, diversity, and joining) recombination of genes that encode for T and B cell receptors. Therefore, mutations in these genes would most likely affect VDJ recombination in the immune system.

Mutations in the Genes for RAG1 and RAG2 Would Most