Mutation in the MutS gene is most commonly associated with
A) colorectal cancer.
B) melanoma.
C) squamous cell carcinoma of the skin.
D) small-cell carcinoma.

Question

Quizplus · Accepted Answer

Mutation in the MutS gene is most commonly associated with colorectal cancer, which is a result of a defect in DNA mismatch repair. MutS is a protein involved in this repair process, and mutations in the MutS gene can disrupt the normal function of this protein, leading to an increased risk of developing colorectal cancer. There is no significant association between MutS mutations and melanoma, squamous cell carcinoma, or small-cell carcinoma.

Mutation in the MutS Gene Is Most Commonly Associated with