The experimental inactivation of a gene by homologous recombination with an inactive mutant to assess function of the normal genes in intact organisms is often referred to as what type of experiment?
A) Transgenic
B) Hybrid
C) Knockout
D) Gain-of-function

Question

Quizplus · Accepted Answer

The experimental inactivation of a gene by homologous recombination with an inactive mutant is commonly referred to as a knockout experiment. Transgenic experiments involve the insertion of a foreign gene into an organism's genome, hybrid experiments refer to the crossing of different strains or species, and gain-of-function experiments involve introducing a mutated or overexpressed gene to observe its effects.

The Experimental Inactivation of a Gene by Homologous Recombination with an Inactive