Which method uses an antibody that recognizes cellular proteins to investigate protein-protein interactions?
A) Immunoprecipitation
B) The yeast two-hybrid system
C) Protein array
D) Electrophoretic mobility shift assay

Question

Quizplus · Accepted Answer

Immunoprecipitation involves the use of an antibody to bind to a specific protein, which can then be isolated and analyzed for interactions with other proteins. The yeast two-hybrid system and protein array also investigate protein-protein interactions, but do not rely on the use of antibodies. The electrophoretic mobility shift assay measures the binding of a protein to a labeled DNA fragment but does not investigate protein-protein interactions.

Which Method Uses an Antibody That Recognizes Cellular Proteins to Investigate