A reaction in which the substrate glucose binds to the enzyme hexokinase and the configuration of both molecules changes is an example of
A) a lock-and-key mechanism.
B) an induced fit mechanism.
C) competitive inhibition.
D) allosteric inhibition.

Question

Quizplus · Accepted Answer

An induced fit mechanism occurs when the substrate binding to the active site of an enzyme causes a conformational change in the enzyme, leading to a better fit between the enzyme and substrate. In this case, the binding of glucose to hexokinase causes a change in the configuration of both molecules, which is characteristic of an induced fit mechanism. A lock-and-key mechanism, on the other hand, suggests that the substrate and enzyme fit together like a lock and key without any changes in conformation. Competitive inhibition and allosteric inhibition involve different mechanisms of enzyme regulation and do not apply to this scenario.

A Reaction in Which the Substrate Glucose Binds to the Enzyme