Which of the following was an important finding of CATIE, a blinded controlled study comparing multiple antipsychotics to replicate "real-world" prescriptions to a representative patient population?

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CATIE found that drug effectiveness is very different under conditions similar to routine clinical practice compared with controlled trials. While newer antipsychotic drugs were not found to be significantly more effective than first-generation drugs, overall rates of drug discontinuation were high, indicating that treatment remains a challenge for patients with schizophrenia.

Which of the Following Was an Important Finding of CATIE