Question 1

A meta-analysis of research published between 2009 and early 2019 suggests that roughly _______ of cannabis users meet the criteria for CUD.

Accepted Answer

The meta-analysis suggests that roughly 20% to 25% of cannabis users meet the criteria for CUD.

Question 2

Recreational synthetic cannabinoids differ from THC in that they are _______ agonists at the CB₁ and CB₂ receptors and have _______ effects.

Accepted Answer

Recreational synthetic cannabinoids are full agonists at the CB1 and CB2 receptors, which means they bind with high affinity and activate these receptors more completely than THC, a partial agonist. This results in more potent effects compared to THC.

Question 3

Distinguish between the various cannabis derivatives including marijuana, hashish, hash oil, and sinsemilla in terms of potency and route of administration.

Accepted Answer

The answer of Distinguish between the various cannabis derivatives including...

Question 4

Describe the historical use of marijuana as agricultural commodity, medicine, and recreational drug. What role did Harry Anslinger and various regulatory policies have on this use in the United States?

Accepted Answer

The answer of Describe the historical use of marijuana as...

Question 5

Describe the factors that influence the amount of THC that is absorbed during smoking and oral administration. Explain why it takes more than two weeks to completely eliminate THC metabolites from the body.

Accepted Answer

The answer of Describe the factors that influence the amount...

Question 6

Describe the discovery of the cannabinoid receptor (CB₁) by two independent research groups. Characterize the receptor in terms of its location in the CNS, probable location within the synapse, and the cellular effects it is responsible for. Identify a CB₁ receptor antagonist that has been used to clarify the role of this receptor.

Accepted Answer

The answer of Describe the discovery of the cannabinoid receptor...

Question 7

Identify the two substances that have been shown to act as endocannabinoids in the CNS. List several characteristics of these substances that make them different from more traditional endogenous transmitter substances like dopamine.

Accepted Answer

The answer of Identify the two substances that have been...

Question 8

Describe the role of endocannabinoids in retrograde signaling in the hippocampus. Be sure to include the role of intracellular Ca²⁺ in your answer.

Accepted Answer

The answer of Describe the role of endocannabinoids in retrograde...

Question 9

What are the four different types of cannabinoids formulations used for medical purposes?

Accepted Answer

The answer of What are the four different types of...

Question 10

Describe the subjective, behavioral, and physiological changes associated with the stages of marijuana use referred to as the "buzz," the "high," and being "stoned." Under what conditions are adverse reactions most likely to occur?

Accepted Answer

The answer of Describe the subjective, behavioral, and physiological changes...

Question 11

Under what circumstances do humans show deficits in cognition and psychomotor performance following acute cannabinoid use?

Accepted Answer

The answer of Under what circumstances do humans show deficits...

Question 12

What scientific evidence shows that humans find cannabinoids reinforcing? Why has it been somewhat more difficult to demonstrate that animals find cannabinoids rewarding? Describe the two typical behavioral paradigms that are used in this research.

Accepted Answer

The answer of What scientific evidence shows that humans find...

Question 13

Describe the neural mechanisms that underlie both the reinforcing and aversive aspects of cannabinoid administration.

Accepted Answer

The answer of Describe the neural mechanisms that underlie both...

Question 14

What is the evidence that marijuana use is a serious national problem that shows little sign of improving or being influenced by current drug control policies? What age group seems to be at the greatest risk for cannabis use?

Accepted Answer

The answer of What is the evidence that marijuana use...

Question 15

Identify several factors that may increase an adolescent's likelihood of using marijuana in the first place or progressing from occasional use to having CUD.

Accepted Answer

The answer of Identify several factors that may increase an...

Question 16

Describe the differences between the marijuana abstinence syndrome in humans and the precipitated withdrawal syndrome reported in animals. What neural systems seem to be responsible for these behavioral changes?

Accepted Answer

The answer of Describe the differences between the marijuana abstinence...

Question 17

Identify two pharmacological treatment approaches and two non-drug treatment approaches for addressing the problems of cannabis dependence. Why are most of these therapies not very successful?

Accepted Answer

The answer of Identify two pharmacological treatment approaches and two...

Question 18

Identify the known effects of chronic cannabis use on health. What areas need to be researched further?

Accepted Answer

The answer of Identify the known effects of chronic cannabis...

Question 19

In animal studies, what types of brain changes have been observed following adolescent exposure to marijuana?

Accepted Answer

The answer of In animal studies, what types of brain...

Quiz 14: Marijuana and the Cannabinoids

A meta-analysis of research published between 2009 and early 2019 suggests that roughly _______ of cannabis users meet the criteria for CUD.

Recreational synthetic cannabinoids differ from THC in that they are _ agonists at the CB₁ and CB₂ receptors and have _ effects.

Distinguish between the various cannabis derivatives including marijuana, hashish, hash oil, and sinsemilla in terms of potency and route of administration.

Describe the historical use of marijuana as agricultural commodity, medicine, and recreational drug. What role did Harry Anslinger and various regulatory policies have on this use in the United States?

Describe the factors that influence the amount of THC that is absorbed during smoking and oral administration. Explain why it takes more than two weeks to completely eliminate THC metabolites from the body.

Identify the two substances that have been shown to act as endocannabinoids in the CNS. List several characteristics of these substances that make them different from more traditional endogenous transmitter substances like dopamine.

Describe the role of endocannabinoids in retrograde signaling in the hippocampus. Be sure to include the role of intracellular Ca²⁺ in your answer.

What are the four different types of cannabinoids formulations used for medical purposes?

Describe the subjective, behavioral, and physiological changes associated with the stages of marijuana use referred to as the "buzz," the "high," and being "stoned." Under what conditions are adverse reactions most likely to occur?

Under what circumstances do humans show deficits in cognition and psychomotor performance following acute cannabinoid use?

What scientific evidence shows that humans find cannabinoids reinforcing? Why has it been somewhat more difficult to demonstrate that animals find cannabinoids rewarding? Describe the two typical behavioral paradigms that are used in this research.

Describe the neural mechanisms that underlie both the reinforcing and aversive aspects of cannabinoid administration.

What is the evidence that marijuana use is a serious national problem that shows little sign of improving or being influenced by current drug control policies? What age group seems to be at the greatest risk for cannabis use?

Identify several factors that may increase an adolescent's likelihood of using marijuana in the first place or progressing from occasional use to having CUD.

Describe the differences between the marijuana abstinence syndrome in humans and the precipitated withdrawal syndrome reported in animals. What neural systems seem to be responsible for these behavioral changes?

Identify two pharmacological treatment approaches and two non-drug treatment approaches for addressing the problems of cannabis dependence. Why are most of these therapies not very successful?

Identify the known effects of chronic cannabis use on health. What areas need to be researched further?

In animal studies, what types of brain changes have been observed following adolescent exposure to marijuana?

Quiz 14: Marijuana and the Cannabinoids

A meta-analysis of research published between 2009 and early 2019 suggests that roughly _______ of cannabis users meet the criteria for CUD.

Recreational synthetic cannabinoids differ from THC in that they are _______ agonists at the CB1 and CB2 receptors and have _______ effects.

Distinguish between the various cannabis derivatives including marijuana, hashish, hash oil, and sinsemilla in terms of potency and route of administration.

Describe the historical use of marijuana as agricultural commodity, medicine, and recreational drug. What role did Harry Anslinger and various regulatory policies have on this use in the United States?

Describe the factors that influence the amount of THC that is absorbed during smoking and oral administration. Explain why it takes more than two weeks to completely eliminate THC metabolites from the body.

Identify the two substances that have been shown to act as endocannabinoids in the CNS. List several characteristics of these substances that make them different from more traditional endogenous transmitter substances like dopamine.

Describe the role of endocannabinoids in retrograde signaling in the hippocampus. Be sure to include the role of intracellular Ca2+ in your answer.

What are the four different types of cannabinoids formulations used for medical purposes?

Describe the subjective, behavioral, and physiological changes associated with the stages of marijuana use referred to as the "buzz," the "high," and being "stoned." Under what conditions are adverse reactions most likely to occur?

Under what circumstances do humans show deficits in cognition and psychomotor performance following acute cannabinoid use?

What scientific evidence shows that humans find cannabinoids reinforcing? Why has it been somewhat more difficult to demonstrate that animals find cannabinoids rewarding? Describe the two typical behavioral paradigms that are used in this research.

Describe the neural mechanisms that underlie both the reinforcing and aversive aspects of cannabinoid administration.

What is the evidence that marijuana use is a serious national problem that shows little sign of improving or being influenced by current drug control policies? What age group seems to be at the greatest risk for cannabis use?

Identify several factors that may increase an adolescent's likelihood of using marijuana in the first place or progressing from occasional use to having CUD.

Describe the differences between the marijuana abstinence syndrome in humans and the precipitated withdrawal syndrome reported in animals. What neural systems seem to be responsible for these behavioral changes?

Identify two pharmacological treatment approaches and two non-drug treatment approaches for addressing the problems of cannabis dependence. Why are most of these therapies not very successful?

Identify the known effects of chronic cannabis use on health. What areas need to be researched further?

In animal studies, what types of brain changes have been observed following adolescent exposure to marijuana?

Recreational synthetic cannabinoids differ from THC in that they are _ agonists at the CB₁ and CB₂ receptors and have _ effects.

Describe the role of endocannabinoids in retrograde signaling in the hippocampus. Be sure to include the role of intracellular Ca²⁺ in your answer.