Himmelsbach's classic model of opiate dependence as a disruption of homeostasis was confirmed physiologically by studying
A) changes in cAMP synthesis.
B) intracerebral injections of opiate antagonists.
C) place aversion for novel environments.
D) mechanisms underlying classical conditioning tolerance.

Question

Quizplus · Accepted Answer

Himmelsbach's model of opiate dependence, which posits that dependence is a disruption of homeostasis, was physiologically confirmed through studies showing changes in cyclic AMP (cAMP) synthesis in response to opiates. This pathway is crucial in understanding how the body attempts to maintain balance in the presence of external substances like opiates.

Himmelsbach's Classic Model of Opiate Dependence as a Disruption of Homeostasis