The hyperexcitability that people with AUD experience during withdrawal could potentially be treated by the NMDA receptor antagonist
A) picrotoxin.
B) biculline.
C) valium.
D) ketamine.

Question

Quizplus · Accepted Answer

Ketamine is an NMDA receptor antagonist that has shown promise in reducing hyperexcitability during alcohol withdrawal. It has been found to reduce withdrawal-induced seizures and decrease alcohol intake in animal models, and there is some evidence to suggest it could be effective in humans as well. Picrotoxin and biculline are GABA antagonists that would likely exacerbate hyperexcitability during withdrawal, while Valium is a benzodiazepine that enhances GABA transmission and is already a commonly used pharmacological treatment for alcohol withdrawal symptoms.

The Hyperexcitability That People with AUD Experience During Withdrawal Could