Which statement regarding 5-HT₃ receptors is false? A) Some of them are located on peripheral terminals of the vagus nerve. B) Activation of these receptors inhibits the vomiting center in the brainstem. C) Drugs that block this receptor subtype are used to treat nausea in cancer chemotherapy patients. D) Ondansetron, granisetron, and palonosetron are all 5-HT₃ receptor antagonists.

Question

Quizplus · Accepted Answer

The correct receptor subtype mentioned in the question seems to be a typographical error. However, assuming it refers to 5-HT3 receptors based on the context of the options provided: Activation of 5-HT3 receptors can actually promote the vomiting reflex, not inhibit it. Drugs like ondansetron, granisetron, and palonosetron are antagonists of the 5-HT3 receptor and are used to prevent nausea and vomiting by blocking the receptor, not activating it.

Which Statement Regarding 5-HT3 Receptors Is False

Which Statement Regarding 5-HT₃ Receptors Is False