Which Type of Drug Administration Would Bypass the Blood-Brain Barrier

Which type of drug administration would bypass the blood-brain barrier?

A) Sublingual administration, which involves placing the drug under the tongue.
B) Subcutaneous administration, in which case the drug is injected into a location just below the skin.
C) Intrathecal injection of anesthetic into the cerebrospinal fluid.
D) Transdermal administration with a skin patch that delivers the drug through the skin