A person weighing 145 lbs ingests a tablet containing 5 mg of a drug. A blood draw shows a Cp,max of 35 mg/L. What is the V_d of this drug in L/kg? Assume that bioavailability is 100%

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Quizplus · Accepted Answer

The volume of distribution (Vd) can be calculated using the formula Vd = Dose / Cp,max. Here, Vd = 5 mg / 35 mg/L = 0.1429 L. To convert this to L/kg, divide by the person's weight in kg (145 lbs = 65.77 kg), resulting in approximately 0.4 L/kg.

A Person Weighing 145 Lbs Ingests a Tablet Containing 5