In ChIP, what sort of molecule is used to isolate chromatin attached to the transcription factor of interest

Question

Quizplus · Accepted Answer

In ChIP (Chromatin Immunoprecipitation), an antibody specific to the transcription factor of interest is used to isolate and pull down chromatin fragments that are bound to the transcription factor, and protein A/G beads are used to immobilize the antibody and the chromatin fragments it has pulled down. Therefore, the molecule used to isolate chromatin attached to the transcription factor of interest is a protein, i.e., the antibody.

In ChIP, What Sort of Molecule Is Used to Isolate