In the experiment that led to Sperry's chemoaffinity hypothesis optic nerve of a frog was severed and then put back in place after being rotated. When the nerve regenerated, the frog's vision was mirror-reversed (as demonstrated by the frog's behavioral responses to stimuli in the eye). What did these results suggest about where the retina reinnervated the tectum, and what directed this reinnervation? What is the chemoaffinity hypothesis that was derived from this result?
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