Question 1

When discussing ophthalmic solutions, which of the following is false?
I. Ophthalmic solutions can be used with contact lenses in place.
II. Patients should pull out the lower eyelid to form a pocket to place ophthalmic drops.
III. Different ophthalmic preparations should be applied at least 10-20 minutes apart.
IV. Ophthalmic solutions have no systemic effects.

Accepted Answer

Statements I and IV and false-contact lenses should be removed before application of ophthalmic solutions and ophthalmic preparations can have systemic effects. Statements II and III are correct.

Question 2

Of the following lab values, which would be true in a case of iron deficiency anemia?

Accepted Answer

Iron deficiency anemia is characterized, in part, by a decreased MCV (Mean Corpuscular Volume), an increased RDW (Reticulocyte Distribution Width), and a decreased MCHC (Mean Corpuscular Hemoglobin Concentration).

Question 3

Which of the following drug classes are used to prevent and treat inflammatory bowel disease (IBD)?
I. Immunosuppressants
II. Gamma amino butyric acid
III. Corticosteroids
IV. Macrolides

Accepted Answer

Immunosuppressants and corticosteroids are commonly used to treat and prevent IBD.

Question 4

Which of the following is an anxiolytic?

Accepted Answer

Buspirone is an anxiolytic. Budenoside is a corticosteroid used as an inhalant for asthma therapy. Busulfan is an alkylating agents used in CML. Bumetanide is a loop diuretic used to control edema of heart failure.

Question 5

Which of the following is an opioid-like agonist?

Accepted Answer

Propoxyphene is the only opioid-like agonist listed. Phenobarbital is a barbiturate and a sedative/hypnotic. Diltiazem is a calcium channel blocker. Pemoline is a CNS stimulant.

Question 6

What is ranitidine used to treat?

Accepted Answer

Ranitidine is marketed as Zantac and is a histamine-2 receptor antagonist used to treat hyperacidity and ulcers.

Question 7

Which of the following conditions is a contraindication for the use of itraconazole?

Accepted Answer

Itraconazole should not be used in a patient with fungal meningitis.

Question 8

Which of the following are not signs/symptoms/complications of lupus-like syndrome?

Accepted Answer

Lupus-like syndrome is a reaction to drug therapy that is characterized by a red, scaly, macular rash, joint pain, and fever. Arrhythmias are not a characteristic of lupus-like syndrome.

Question 9

A 56-year-old female patient has a diagnosis of GERD, mild hypertension, hyperthyroidism, hypercholesterolemia, and Type II diabetes of 5 years duration. Medications include metformin, glyburide, propylthiouracil, lansoprazole, atorvastatin, and hydrochlorothiazide. Recent labs report an A1c of 9.8%, TSH of 2.7, Hgb of 12.2 and total cholesterol of 130mg/dL. A physical exam reveals a blood pressure of 128/76 and a resting heart rate of 98. The patient is complaining of muscle cramps, fatigue, and thirst. Which of the following medications may need adjustment?

Accepted Answer

The patient is showing signs and symptoms of uncontrolled diabetes (A1c increased thirst) and an adverse effect of statin use (muscle cramps, fatigue). Thyroid tests are within normal limits. The hypoglycemics and statin dosages should be adjusted.

Question 10

What is the mechanism of action of loratadine (Alavert/Claritin)?

Accepted Answer

Loratadine is a 2nd generation H-1 antagonist and blocks the peripheral effects of histamine release.

Question 11

Which of the following chemical modifications would likely increase the water solubility of a drug?

Accepted Answer

Amorphous forms have greater solubility than crystalline forms. Anhydrous (without water) compounds have greater solubility than when they become hydrated. Lipophilic indicates "fat-loving," so a lipophilic side group would decrease solubility as would the removal of a hydroxyl (-OH) group.

Question 12

Droperidol is used to treat ______ and is contraindicated with/in _____.

Accepted Answer

Droperidol is an anti emetic and general anesthetic of the butyrophenone class. It is mainly used to control perioperative nausea and vomiting and is contraindicated in patients with increased QT interval of greater than 440msec in males and 450msec in females.

Question 13

Ipratropium is a _____ used to treat _____ and which rarely has the adverse effect of inducing ______.

Accepted Answer

Ipratropium is a bronchodilator and an anti-cholinergic (not an agonist) agent and is used to treat COPD (Chronic Obstructive Pulmonary Disease) and asthma. A rare adverse effect is cardiac arrhythmia. It is marketed as Atrovent.

Question 14

Which of the following are possible adverse effects of ramipril (Altace)?
I. Heart failure and hyperkalemia
II. Angioedema and bronchospasm
III. Respiratory depression and coma
IV. Paradoxical acid reflux and esophagitis

Accepted Answer

Ramipril is an Angiotensin Converting Enzyme (ACE) Inhibitor. Adverse effects include heart failure, MI, hyperkalemia, angioedema, bronchospasm, anaphylaxis, and agranulocytosis.

Question 15

Which of the following brand names is not correctly matched with its generic name?

Accepted Answer

The brand name of venlafaxine is Effexor. Levitra is the brand name of vardenafil. The others are correctly matched.

Question 16

Which of the following is a "high-alert" drug meaning, they can cause significant harm when used in error?

Accepted Answer

Of the agents listed, amiodorone, IV has significant potential for harm.
Amiodarone injection is used to treat life-threatening heart rhythm problems called ventricular arrhythmias. 
In the US, it can be sold under the brand name Cordarone IV.
Amiodarone is typically used in patients who have already been treated with other cardiac medicines that did not work well.
Amiodarone injection belongs to the group of medicines known as antiarrhythmics. It works directly on the heart tissue and will slow the nerve impulses in the heart. This helps keep the heart rhythm regular but can cause great harm if misused.

Question 17

Rifapentine is a(n) _____ used to treat ______ and which rarely has the adverse effect of inducing _______.

Accepted Answer

Rifapentine is a rifamycin derivative antitubercular agent. It can induce neutropenia and leucopenia as well as pancreatitis and hyperkalemia.

Question 18

A patient taking sulfasalazine should be told which of the following?
I. Take sulfasalazine with food
II. Sulfasalazine may turn tears, urine, and sweat orange
III. Sulfasalazine may induce photosensitivity
IV. Take sulfasalazine on an empty stomach

Accepted Answer

Sulfasalazine should be taken with food, can induce photosensitivity, and may turn body fluids an orange color.

Question 19

Which of the following drugs is contraindicated in a pregnant woman?
I. Isotretoin
II. Reloxifene
III. Misoprostol
IV. Loperamide

Accepted Answer

All are Pregnancy Category X drugs except loperamide and are contraindicated during pregnancy.

Question 20

Which of the following forms is meclizine available in? I. IM injectable
II) IV injectable
III) Tablets
IV) Topical cream

Accepted Answer

Meclizine is available only as a tablet form. It is an anticholinergic used to treat motion sickness and vertigo and is marketed as Antivert, Bonamine, and Dramamine.

Quiz 1: Pharmacy Technician Certification

Of the following lab values, which would be true in a case of iron deficiency anemia?

Which of the following drug classes are used to prevent and treat inflammatory bowel disease (IBD) ? I. Immunosuppressants II. Gamma amino butyric acid III. Corticosteroids IV. Macrolides

Which of the following is an anxiolytic?

Which of the following is an opioid-like agonist?

What is ranitidine used to treat?

Which of the following conditions is a contraindication for the use of itraconazole?

Which of the following are not signs/symptoms/complications of lupus-like syndrome?

What is the mechanism of action of loratadine (Alavert/Claritin) ?

Which of the following chemical modifications would likely increase the water solubility of a drug?

Droperidol is used to treat __ and is contraindicated with/in _.

Ipratropium is a ___ used to treat _ and which rarely has the adverse effect of inducing ____.

Which of the following are possible adverse effects of ramipril (Altace) ? I. Heart failure and hyperkalemia II. Angioedema and bronchospasm III. Respiratory depression and coma IV. Paradoxical acid reflux and esophagitis

Which of the following brand names is not correctly matched with its generic name?

Which of the following is a "high-alert" drug meaning, they can cause significant harm when used in error?

Rifapentine is a(n) _ used to treat and which rarely has the adverse effect of inducing _____.

A patient taking sulfasalazine should be told which of the following? I. Take sulfasalazine with food II. Sulfasalazine may turn tears, urine, and sweat orange III. Sulfasalazine may induce photosensitivity IV. Take sulfasalazine on an empty stomach

Which of the following drugs is contraindicated in a pregnant woman? I. Isotretoin II. Reloxifene III. Misoprostol IV. Loperamide

Which of the following forms is meclizine available in? I. IM injectable II) IV injectable III) Tablets IV) Topical cream