Question 1

Which of the following drugs is a histamine blocker and reduces levels of gastric acid?

Accepted Answer

Cimetidine is a histamine receptor antagonist which actively reduces levels of gastric HCl. Hence, it is frequently used in the treatment of peptic ulcers.

Question 2

What class of drugs is recommended as the first line therapy for hypercholesterolemia, after lifestyle modifications?

Accepted Answer

The statins work by blocking an enzyme, HMG-CoA reductase that is the rate-limiting step in the manufacture of cholesterol. Statins reduce LDL-cholesterol, total cholesterol, and triglycerides and slightly increase high-density lipoprotein (HDL-c).

Question 3

Which of the following diseases Acyclovir is the drug of choice for?

Accepted Answer

Acyclovir (Zovirax) is specific for herpes virus infections. It is excreted unchanged in the urine and, therefore, must be used cautiously in the presence of renal impairment.

Question 4

Which of the following drugs is the drug of choice to decrease uric acid levels?

Accepted Answer

Allopurinol is an anti-gout drug that decreases uric acid formation.

Question 5

If the patient is not allergic, what medication is the drug of choice for chlamydia?

Accepted Answer

Azithromycin or Doxycycline should be used to treat the sexually transmitted disease, Chlamydia. Ceftioxone, a cephalosporin is not active against Chlamydia nor is the anti fungal, Metronidazole, and Amoxicillin is resistant to most gram-negative infections.

Question 6

If the patient is not allergic, what medication is the drug of choice for strep pharyngitis?

Accepted Answer

Penicillin is still the drug of choice for most strep pharyngitis. Tetracycline is not active against most strep infections and Acyclovir is an antiviral drug while Metronidazole is an anti-fungal.

Question 7

The nonsteroidal anti-inflammatory drugs (NSAIDs) are beneficial in treating arthritis because they:

Accepted Answer

NSAIDS irreversibly inhibits cyclooxygenase, the enzyme responsible for prostaglandin synthesis. Prostaglandin triggers inflammation.

Question 8

What kind of ulcers is usually formed as a result of chroinic usage of nonsteroidal anti-inflammatory drugs?

Accepted Answer

Nonsteroidal anti-inflammatory drugs primarily cause gastric ulcers.

Question 9

Infective endocarditis frequently occurs in injection drug users. Which of the following valves is most often involved?

Accepted Answer

The tricuspid valve is more frequently involved than the other valves, perhaps because of its nearness to the injection sites.

Question 10

Which of the following medications is most commonly used in the management of Parkinson's disease?

Accepted Answer

The drug of choice in managing Parkinson's disease is Sinemet. This drug is a combination of Carbidopa and Levodopa, which restores dopamine to the brain.

Question 11

Which of the following medications is most likely to be used in managing patients with eating disorders?

Accepted Answer

An antidepressant, such as Prozac, has been found helpful in increasing the rate of weight gain and decreasing relapse occurrence.

Question 12

Which of the following medications is an angiotensin-converting enzyme inhibitor?

Accepted Answer

Captopril is an angiotensin-converting enzyme inhibitor. The other options are calcium channel blockers.

Question 13

If a patient has recently experienced a (MI) within the last 4 hours, which of the following medications would most like be administered?

Accepted Answer

If a patient has recently experienced a (MI) within the last 4 hours, Streptokinase (being a clot busting drug) is the best choice in this situation.

Question 14

The nurse is about to administer digoxin (Lanoxin). Which of the following landmarks is the correct area for obtaining an apical pulse?

Accepted Answer

The correct landmark for obtaining an apical pulse is on the left, intercostal space, midclavicular line. The left, second intercostal space, midclavicular line is the area where the pulmonic valve is auscultated.

Quiz 3: Physician Assistants