Exhibit 10A Consider the following diagrams showing a replication fork moving from left to right. The thick lines represent the template/parental strands. The 5' and 3' represent the ends of those template/parental strands.

-Refer to Exhibit 10A. Which Okazaki fragment was synthesized earliest?
A) A
B) B
C) C
D) D

Question

Exhibit 10A Consider the following diagrams showing a replication fork moving from left to right. The thick lines represent the template/parental strands. The 5' and 3' represent the ends of those template/parental strands.
 
-Refer to Exhibit 10A. Which Okazaki fragment was synthesized earliest?
A) A 
B) B 
C) C 
D) D

Quizplus · Accepted Answer

The Okazaki fragment A was synthesized earliest because it is closest to the replication origin and replication proceeds bidirectionally from there. As replication proceeds further from the origin, newer Okazaki fragments are synthesized in a sequential manner.

Exhibit 10A Consider the Following Diagrams Showing a Replication Fork