Thalidomide has historically been associated with teratogenesis. It is still used for some conditions. Which of the following conditions is thalidomide used for (on- or off-label)? I. Bipolar disorder
II. HIV associated wasting syndrome
III. Erythema nodosum leprosum(ENL)
IV. Post-menopausal bleeding

Question

Quizplus · Accepted Answer

Thalidomide is an immunomodulator and an angiogenesis inhibitor. It is used on-label for ENL and off-label for HIV associated wasting syndrome. There is no rationale to use it for either bipolar disorder or post-menopausal bleeding.

Thalidomide Has Historically Been Associated with Teratogenesis