Patients taking protease inhibitors should avoid drinking large amounts of grapefruit juice because it ____________ CYP_____________ and ____________ blood levels of the drug.

Question

Quizplus · Accepted Answer

Ingesting large amounts of grapefruit juice inhibits the enzyme CYP3A4. CYP3A4 is involved in the metabolism of protease inhibitors-thus, grapefruit juice would increase the serum levels of the drug.

Patients Taking Protease Inhibitors Should Avoid Drinking Large Amounts of Grapefruit