Regarding receptor regulation
A) Receptor down regulation occurs over hours - days
B) Receptor responses to drugs often "desensitise" with time - this desensitisation is usually irreversible
C) The mechanism of agonist induced desensitisation of the nicotinic Ach receptor has been worked out in detail
D) All "internalised" receptors are degraded by lysosomes
E) None of the above are correct
Correct Answer:
Verified
Q4: A D Response B C Concentration Which
Q5: EC50 is
A)Measured with a radioactive receptor
B)Always equal
Q6: Which of the following will NOT alter
Q7: Volume of distribution equals
A)Dose given/plasma concentration
B)Total amount
Q8: Which of the following drugs undergoes rate
Q9: Ligand gated channel receptors include all of
Q11: Which of the following acts on intracellular
Q12: Which of the following has ? bioavailability
Q13: First order kinetics
A)Means rate of reaction is
Q14: A single compartment model means that
A)One exponential
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