Question 1

Enteric coated tablet is dissolved in 0.1 N HCl as per I.P.
A)180 minutes
B)120 minutes
C)45 minutes
D)60 minutes

Accepted Answer

Enteric coated tablets are designed to dissolve in the intestine, not the stomach. According to the Indian Pharmacopoeia (I.P.), the dissolution test for enteric coated tablets specifies that they should not dissolve in 0.1 N HCl for the first 2 hours (120 minutes), simulating the acidic environment of the stomach.

Question 2

During compression, entrapped air may lead to:
A)Capping & lamination
B)Picking & sticking
C)Binding & sticking
D)Ejection & Removal

Accepted Answer

Capping and lamination can occur during the compression process if air is entrapped in the tablet, as it prevents proper compaction and bonding of the material.

Question 3

Anhydrous lactose has advantage over hydrous lactose.
A)Improved flow
B)Absence of milliard reaction
C)Improved Compressibility
D)High microbial load

Accepted Answer

B

Question 4

If the dose of the drug is inadequate, then it generally requires the following one, to make up its bulk:
A)Binders
B)Disintegrants
C)Lubricants
D)Diluents

Accepted Answer

Diluents are used to increase the bulk volume of a drug when the dose is too small to be handled conveniently. This helps in making the drug easier to process and consume.

Question 5

The first and most widely used diluent in tablet formulation is
A)Dextrose
B)Lactose
C)MCC
D)Starch

Accepted Answer

Lactose is the first and most widely used diluent in tablet formulation due to its excellent compressibility and cost-effectiveness.

Question 6

Which of the following is a synthetic adhesive?
A)PVP
B)MC
C)HPMC
D)HPC

Accepted Answer

Polyvinylpyrrolidone (PVP) is a synthetic adhesive, while the others are cellulose derivatives used as thickeners or stabilizers.

Question 7

Which of the following packaging is commonly used for packaging of capsules?
A)Blister
B)Strip
C)Both
D)None

Accepted Answer

Capsules are commonly packaged in both blister and strip packaging to protect them from external factors and for ease of use.

Question 8

Which of the following is used to fill powdered dry solid into soft gelatin capsules?
A)Accogel
B)Rotofil
C)Rotosort
D)Rotoweigh

Accepted Answer

Accogel is the machine used for filling powdered dry solids into soft gelatin capsules, specifically designed for this purpose.

Question 9

Sealing of capsules is achieved by:
A)100 °C
B)20 °C
C)37 °C - 40 °C
D)70 °C

Accepted Answer

Sealing of capsules is typically achieved at a temperature range of 37 °C - 40 °C, which is sufficient to soften the gelatin and allow the two halves of the capsule to fuse together.

Question 10

Find the correct one.
A)000 largest size
B)00 Largest size
C)5 smallest size
D)Both A and C are correct

Accepted Answer

In the context of clothing, needles, or other items where sizing conventions are used, "000" is often larger than "00", and "5" could indeed be considered a smaller size. Therefore, both statements A and C are correct, making D the correct choice.

Question 11

Which is a capsule filling machine?
A)Osaka
B)Jaansan
C)Macofar
D)All of the above

Accepted Answer

Macofar is specifically known for manufacturing capsule filling machines, but Osaka and Jaansan also produce equipment used in the pharmaceutical industry, including capsule filling machines. Therefore, all the options listed are associated with the production of capsule filling machines.

Question 12

Iron content of gelatin for hard and soft gelatin capsule:
A)NMT 5 ppm
B)NMT 10 ppm
C)NMT 25 ppm
D)NMT 15 ppm

Accepted Answer

The answer of Iron content of gelatin for hard and...

Question 13

Gelatin is hydrolysed product:
A)Pectin
B)Tannin
C)Shellac
D)Collagen

Accepted Answer

Gelatin is a hydrolysed product of collagen, which is found in the skin, bones, and connective tissues of animals.

Question 14

Moisture content of capsule is determined by:
A)IR Spectroscopy
B)Toulene distillation method
C)Accogel machine
D)Erweka key

Accepted Answer

The toluene distillation method is a common technique used to determine the moisture content in capsules.

Question 15

____________ treatment is used for the solubility of gelatin.
A)Heat
B)Formalin
C)Alcohol
D)Formalin.

Accepted Answer

Formalin treatment is used to decrease the solubility of gelatin in water, making it less soluble. This process is often used in the preparation of gelatin capsules in pharmaceuticals to make them more resistant to humidity and other conditions that might otherwise cause them to dissolve too quickly.

Question 16

Type A gelatin has its isoelectric point in the region of
A)pH 4.7
B)pH 9.0
C)pH 7.4
D)pH 9.4

Accepted Answer

Type A gelatin is derived from acid-treated collagen and typically has an isoelectric point around pH 9.0.

Question 17

In capsules, Elancofil and accofil machine is used for
A)Filling of powder into capsules
B)Filling pellets into capsules
C)Sorting filled capsule
D)Filling liquids into capsules

Accepted Answer

Elancofil and accofil machine is used for filling powder into capsules.

Question 18

In capsules, Qualiseal machine is used for:
A)Sorting the filled capsules
B)Filling the liquids into capsules
C)Filling pellets into capsules
D)Filling powder into capsules

Accepted Answer

The answer of In capsules, Qualiseal machine is used for:
A)Sorting...

Question 19

Sulphur dioxide is used for:
A)As a coloring agent
B)To prevent bitterness
C)To prevent decomposition of gelatin shell
D)None of the above

Accepted Answer

Sulphur dioxide acts as a preservative and is used to prevent the decomposition of the gelatin shell in various pharmaceutical and food products, helping to maintain their quality and extend their shelf life.

Question 20

Green bones are used for the preparation of gelatin of the type:
A)Type A
B)Type B
C)Type C
D)A & B

Accepted Answer

Green bones are used for the preparation of Type B gelatin. Type B gelatin is derived from alkaline pretreatment of collagen, which is the process used for green bones.

Quiz 3: Tablets, Capsules, and Dosage Forms

Enteric coated tablet is dissolved in 0.1 N HCl as per I.P.

During compression, entrapped air may lead to:

Anhydrous lactose has advantage over hydrous lactose.

If the dose of the drug is inadequate, then it generally requires the following one, to make up its bulk:

The first and most widely used diluent in tablet formulation is

Which of the following is a synthetic adhesive?

Which of the following packaging is commonly used for packaging of capsules?

Which of the following is used to fill powdered dry solid into soft gelatin capsules?

Sealing of capsules is achieved by:

Find the correct one.

Which is a capsule filling machine?

Iron content of gelatin for hard and soft gelatin capsule:

Gelatin is hydrolysed product:

Moisture content of capsule is determined by:

____________ treatment is used for the solubility of gelatin.

Type A gelatin has its isoelectric point in the region of

In capsules, Elancofil and accofil machine is used for

In capsules, Qualiseal machine is used for:

Sulphur dioxide is used for:

Green bones are used for the preparation of gelatin of the type: